Castle Biosciences, Inc. (CSTL)

Castle Biosciences (Nasdaq: CSTL) is a leading diagnostics company improving health through innovative tests that guide patient care. With a primary focus in dermatologic and gastroenterological disease, we develop personalized, clinically actionable solutions that help improve disease management and patient outcomes.

We put people first—empowering patients and clinicians and informing care decisions through rigorous science and advanced molecular tests that support more confident treatment planning.

View Executive Team & Board of Directors

Learn more about Castle Biosciences' mission to empower patients and healthcare providers by combining innovation, advanced technologies and relevant real-world evidence to address critical unmet clinical needs and improve health outcomes.

Video Transcript

Learn more about Castle Biosciences' mission to empower patients and healthcare providers by combining innovation, advanced technologies and relevant real-world evidence to address critical unmet clinical needs and improve health outcomes.

This behind-the-scenes video offers an inside look at Castle Biosciences' TissueCypher testing process, showcasing how advanced imaging, multiplexed biomarker staining and AI-driven analysis are utilized to assess a patient's risk of progression from Barrett’s esophagus to esophageal cancer.

Video Transcript

This behind-the-scenes video offers an inside look at Castle Biosciences' TissueCypher testing process, showcasing how advanced imaging, multiplexed biomarker staining and AI-driven analysis are utilized to assess a patient's risk of progression from Barrett’s esophagus to esophageal cancer.

Castle at a Glance

A leader in precision diagnostics in Dermatology and Gastroenterology
6 commercially available tests with ~$36 billion U.S. total addressable market (TAM)
883 full-time employees across U.S. (as of Dec. 31, 2025)
CAP/CLIA-certified labs in Phoenix & Pittsburgh
Collectively, ~158 peer-reviewed articles have been published demonstrating the analytical validity, clinical validity and clinical utility of the tests in our portfolio (2025)

Featured Report

2025 Annual Report

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IR Contacts

Headquarters

Castle Biosciences, Inc.
1500 West Parkwood Avenue
Suite 400
Friendswood, TX 77546
T: 866-788-9007

Investor Relations

IR@castlebiosciences.com

Transfer Agent

Broadridge Corporate Issuer Solutions, Inc.
Phone: 720-378-5591
Shareholder@broadridge.com
https://shareholder.broadridge.com